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Life Sciences

GxP

Good Practice Regulations (GMP, GLP, GCP)

FDA and international regulations ensuring quality and safety in pharmaceutical, medical device, and clinical research.

What is GxP?

GxP is a general abbreviation for Good (x) Practice quality guidelines and regulations. The "x" represents the specific field: GMP (Good Manufacturing Practice), GLP (Good Laboratory Practice), GCP (Good Clinical Practice), GDP (Good Distribution Practice), and others. These regulations ensure that products are safe, meet quality requirements, and that clinical trials are conducted ethically.

GxP regulations are enforced by FDA in the US and equivalent agencies globally (EMA, MHRA, PMDA, etc.). Compliance requires implementing quality systems, documentation practices, personnel training, facility controls, and validation appropriate to the specific GxP discipline.

Who Needs GxP?

  • Pharmaceutical manufacturers (GMP)
  • Preclinical testing labs (GLP)
  • Clinical trial sponsors and sites (GCP)
  • Medical device manufacturers
  • Pharmaceutical distributors (GDP)

Key Requirements

Core compliance areas for GxP

1

Quality System

Establish and maintain quality management system appropriate to activities.

2

Documentation

Maintain complete, accurate documentation of all GxP activities.

3

Personnel Qualification

Ensure personnel are trained and qualified for their responsibilities.

4

Facility and Equipment

Maintain facilities and equipment in qualified, controlled state.

5

Validation

Validate processes, methods, and computerized systems.

Benefits of GxP Compliance

  • Regulatory approval for products
  • Patient safety protection
  • Product quality assurance
  • Market authorization
  • Global regulatory acceptance
  • Foundation for life sciences operations

How PartnerAlly Helps with GxP

Streamline your path to GxP compliance with our AI-powered platform.

GxP compliance assessment
Quality system documentation
Training tracking and management
Validation protocol templates
Deviation and CAPA management
Inspection preparation